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Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/36755
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dc.contributor.authorMoreira, Xavierpt_PT
dc.contributor.authorSantos, Patríciapt_PT
dc.contributor.authorFaustino, M. Amparo F.pt_PT
dc.contributor.authorRaposo, M. Manuela M.pt_PT
dc.contributor.authorCosta, Susana P.G.pt_PT
dc.contributor.authorMoura, Nuno M.M.pt_PT
dc.contributor.authorGomes, Ana T.P.C.pt_PT
dc.contributor.authorAlmeida, Adelaidept_PT
dc.contributor.authorNeves, M.G.P.M.S.pt_PT
dc.date.accessioned2023-03-30T15:20:17Z-
dc.date.available2023-03-30T15:20:17Z-
dc.date.issued2020-07-
dc.identifier.issn0143-7208pt_PT
dc.identifier.urihttp://hdl.handle.net/10773/36755-
dc.description.abstractNew porphyrin-imidazole derivatives were synthesised by Radziszewski reaction between 2-formyl-5,10,15,20-tetraphenylporphyrin 1 and several (hetero)aromatic 1,2-diones, which after cationization afforded promising monocationic photosensitizers 3a-d. Singlet oxygen studies have demonstrated that all the cationic porphyrin-imidazole conjugates 3a–d were capable to produce cytotoxic species. These photosensitizers were able to photoinactivate Eschericha coli and their inactivation profile was improved in the presence of KI.pt_PT
dc.language.isoengpt_PT
dc.publisherElsevierpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FQUI%2F00062%2F2019/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FAMB%2F50017%2F2019/PTpt_PT
dc.relationQUI/UI0686/2018pt_PT
dc.relationREF.-048-88-ARH/2018pt_PT
dc.rightsopenAccesspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectPorphyrinpt_PT
dc.subjectN-Heterocyclespt_PT
dc.subjectPhotosensitizerpt_PT
dc.subjectAntimicrobial photodynamic therapypt_PT
dc.subjectGram-negative E. colipt_PT
dc.titleAn insight into the synthesis of cationic porphyrin-imidazole derivatives and their photodynamic inactivation efficiency against Escherichia colipt_PT
dc.typearticlept_PT
dc.description.versionpublishedpt_PT
dc.peerreviewedyespt_PT
degois.publication.titleDyes and Pigmentspt_PT
degois.publication.volume178pt_PT
dc.identifier.doi10.1016/j.dyepig.2020.108330pt_PT
dc.identifier.essn1873-3743pt_PT
dc.identifier.articlenumber108330pt_PT
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