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Advances in cell-rich inks for biofabricating living architectures

Advancing biofabrication toward manufacturing living constructs with well-defined architectures and increasingly biologically relevant cell densities is highly desired to mimic the biofunctionality of native human tissues. The formulation of tissue-lik...

Photocrosslinkable microgels derived from human platelet lysates: injectable biomaterials for cardiac cell culture

Cardiovascular diseases are a major global cause of morbidity and mortality, and they are often characterized by cardiomyocytes dead that ultimately leads to myocardial ischemia (MI). This condition replaces functional cardiac tissue wit...

Human platelet lysate-derived nanofibrils as building blocks to produce free-standing membranes for cell self-aggregation

Amyloid-like fibrils are garnering keen interest in biotechnology as supramolecular nanofunctional units to be used as biomimetic platforms to control cell behavior. Recent insights into fibril functionality have highlighted their importance ...

A self‐sustaining hydrogels with autonomous supply of nutrients and bioactive domains for 3D cell culture

Photo-crosslinkable platelet lysate (PL)-based hydrogels have been proven to support human-derived cell cultures owing to their high content of bioactive molecules, such as cytokines and growth factors. As a unique self-maintained and bi...