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http://hdl.handle.net/10773/28295
Title: | Computational and statistical methodologies for ORFeome primary structure analysis |
Author: | Moura, Gabriela Pinheiro, Miguel Freitas, Adelaide Valente Oliveira, José Luís Santos, Manuel A. S. |
Keywords: | Genome ORFeome Gene primary structure Codon context Codon usage |
Issue Date: | 2007 |
Publisher: | Humana Press |
Abstract: | Codon usage and context are biased in open reading frames (ORFs) of most genomes. Codon usage is largely influenced by biased genome G+C pressure, in particular in prokaryotes, but the general rules that govern the evolution of codon context remain largely elusive. In order to shed new light into this question we have developed computational, statistical and graphical tools for analysis of codon context on an ORFeome wide scale. In here, we describe these methodologies in detail and show how they can be used for analysis of ORFs of any genome sequenced. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/28295 |
DOI: | |
ISBN: | 978-1-58829-693-1 |
Appears in Collections: | CESAM - Capítulo de livro DETI - Artigos DBio - Artigos DMat - Artigos IEETA - Artigos |
Files in This Item:
File | Description | Size | Format | |
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Mouraetal_and_figs.pdf | 537.11 kB | Adobe PDF | View/Open |
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