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http://hdl.handle.net/10773/20358
Título: | Do bacterial cellulose membranes have potential in drug-delivery systems? |
Autor: | Silvestre, Armando J. D. Freire, Carmen S. R. Neto, Carlos P. |
Palavras-chave: | BIOMIMETIC MINERALIZATION SYNTHESIS SILVER NANOPARTICLES MICROBIAL CELLULOSE CONTROLLED-RELEASE IN-VITRO MECHANICAL-PROPERTIES ACETOBACTER-XYLINUM CALCIUM PHOSPHATES GLUCONACETOBACTER-SACCHARI BIOMEDICAL APPLICATIONS |
Data: | 2014 |
Editora: | INFORMA HEALTHCARE |
Resumo: | Introduction: Bacterial cellulose (BC) is an extremely pure form of cellulose, which, due to its unique properties, such as high purity, water-holding capacity, three-dimensional nanofibrilar network, mechanical strength, biodegradability and biocompatibility, shows a high potential as nanomaterial in a wide range of high-tech domains including biomedical applications, and most notably in controlled drug-delivery systems. Areas covered: This appraisal is intended to cover the major characteristics of BC, followed by the key aspects of BC production both in static and agitated conditions, and a glance of the major applications of BC, giving some emphasis to biomedical applications. Finally, a detailed discussion of the different applications of BC in controlled drug-delivery systems will be put forward, with focus on topical and oral drug-delivery systems, using either native BC or composite materials thereof. Expert opinion: The limited number of studies carried out so far demonstrated that BC, or materials prepared from it, are interesting materials for drug-delivery systems. There is, however, a large field of systematic research ahead to develop new and more selectively responsive materials and eventually to conjugate them with other biomedical applications of BC under development. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/20358 |
DOI: | 10.1517/17425247.2014.920819 |
ISSN: | 1742-5247 |
Versão do Editor: | 10.1517/17425247.2014.920819 |
Aparece nas coleções: | CICECO - Artigos |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Do bacterial cellulose membranes have potential in drug-delivery systems_10.151717425247.2014.920819.pdf | 277.98 kB | Adobe PDF |
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