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http://hdl.handle.net/10773/19295
Título: | NMR metabolomics of human blood and urine in disease research |
Autor: | Duarte, Iola F. Diaz, Silvia O. Gil, Ana M. |
Palavras-chave: | NUCLEAR-MAGNETIC-RESONANCE INFLAMMATORY-BOWEL-DISEASE MAJOR DEPRESSIVE DISORDER POLYCYSTIC-OVARY-SYNDROME CHRONIC KIDNEY-DISEASE H-1-NMR SPECTROSCOPY COLORECTAL-CANCER HEPATOCELLULAR-CARCINOMA BREAST-CANCER METABONOMIC SIGNATURE |
Data: | 2014 |
Editora: | ELSEVIER SCIENCE BV |
Resumo: | This paper reviews the main applications of NMR metabolomics of blood and urine in disease research, over the last 5 years. The broad range of disease types addressed attests the increasing interest within the academic and medical communities to explore the recognised potential of metabolomics to (1) provide insight into underlying disease pathogenesis and (2) unveil new metabolic markers for disease diagnosis and follow up. Importantly, most recent studies reveal an increasing awareness of possible limitations and pitfalls of the metabolomics approach, together with efforts for improved study design and statistical validation, which are crucial requisites for the sound development of NMR metabolomics and its progress into the clinical setting. (C) 2013 Elsevier B.V. All rights reserved. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/19295 |
DOI: | 10.1016/j.jpba.2013.09.025 |
ISSN: | 0731-7085 |
Versão do Editor: | 10.1016/j.jpba.2013.09.025 |
Aparece nas coleções: | CICECO - Artigos |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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NMR metabolomics of human blood and urine in disease research_10.1016j.jpba.2013.09.025.pdf | 434.5 kB | Adobe PDF |
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