Comparative study between the toxicity of 3,4-dichloroaniline and sodium-bromide with 21-days chronic test and using lactate-dehydrogenase activity of Daphnia magna Straus

Abstract

We studied the effect of 3,4-dichloroaniline (DCA) and sodium bromide (NaBr) on the lactate dehydrogenase (LDH) activity in homogenate of Daphnia magna Straus cultured during 21 days in the presence of several concentrations of each chemical. The activity of LDH increased at concentrations of 10 mug/l of DCA and 19 mg/l of NaBr. These concentrations correspond to LOEC values obtained in 21-day chronic tests with Daphnia magna, which suggests that LDH activity may be used as a faster indicator of toxicity in tests with D. magna.