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http://hdl.handle.net/10773/37736
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DC Field | Value | Language |
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dc.contributor.author | Ben-Arfa, Basam A. E. | pt_PT |
dc.contributor.author | Neto, Sofia | pt_PT |
dc.contributor.author | Miranda Salvado, Isabel M. | pt_PT |
dc.contributor.author | Pullar, Robert C. | pt_PT |
dc.contributor.author | Ferreira, José M. F. | pt_PT |
dc.date.accessioned | 2023-05-15T15:15:27Z | - |
dc.date.available | 2023-05-15T15:15:27Z | - |
dc.date.issued | 2019-03-15 | - |
dc.identifier.issn | 1742-7061 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10773/37736 | - |
dc.description.abstract | This research details the successful fabrication of scaffolds by robocasting from high silica sol-gel glass doped with Cu2+ or La3+. The parent HSSGG composition within the system SiO2-CaO-Na2O-P2O5 [67% Si - 24% Ca - 5% Na - 4% P (mol%)] was doped with 5 wt% Cu2+ or La3+ (Cu5 and La5). The paper sheds light on the importance of copper and lanthanum in improving the mechanical properties of the 3-D printed scaffolds. 1 h wet milling was sufficient to obtain a bioglass powder ready to be used in the preparation of a 40 vol% solid loading paste suitable for printing. Moreover, Cu addition showed a small reduction in the mean particle size, while La exhibited a greater reduction, compared with the parent glass. Scaffolds with macroporosity between 300 and 500 µm were successfully printed by robocasting, and then sintered at 800 °C. A small improvement in the compressive strength (7-18%) over the parent glass accompanied the addition of La. However, a much greater improvement in the compressive strength was observed with Cu addition, up to 221% greater than the parent glass, with compressive strength values of up to ∼14 MPa. This enhancement in compressive strength, around the upper limit registered for human cancellous bones, supports the potential use of this material in biomedical applications. STATEMENT OF SIGNIFICANCE: 3D porous bioactive glass scaffolds with greatly improved compressive strength were fabricated by robocasting from a high silica sol-gel glasses doped with Cu2+ or La3+. In comparison to the parent glass, the mechanical performance of scaffolds was greatly improved by copper-doping (>220%), while a modest increase of ∼9% was registered for lanthanum-doping. Doping ions (particularly La3+) acted as glass modifiers leading to less extents of silica polymerisation. This favoured the milling of the glass powders and the obtaining of smaller mean particle sizes. Pastes with a high solid loading (40 vol%) and with suitable rheological properties for robocasting were prepared from all glass powders. Scaffolds with dimensions of 3 × 3 × 4 mm and macro-pore sizes between 300 and 500 µm were fabricated. | pt_PT |
dc.language.iso | eng | pt_PT |
dc.publisher | Elsevier | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/Investigador FCT/IF%2F00681%2F2015%2FCP1302%2FCT0005/PT | pt_PT |
dc.relation | PTDC/EPH–PAT/6281/2014 | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FCTM%2F50011%2F2013/PT | pt_PT |
dc.rights | openAccess | pt_PT |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
dc.subject | Sol-gel | pt_PT |
dc.subject | Bioactive glass | pt_PT |
dc.subject | Compressive strength | pt_PT |
dc.subject | Particle size distribution | pt_PT |
dc.subject | Lanthanum ions | pt_PT |
dc.subject | Copper ions | pt_PT |
dc.title | Robocasting of Cu2+ & La3+ doped sol-gel glass scaffolds with greatly enhanced mechanical properties: compressive strength up to 14 MPa | pt_PT |
dc.type | article | pt_PT |
dc.description.version | published | pt_PT |
dc.peerreviewed | yes | pt_PT |
degois.publication.firstPage | 265 | pt_PT |
degois.publication.lastPage | 272 | pt_PT |
degois.publication.title | Acta biomaterialia | pt_PT |
degois.publication.volume | 87 | pt_PT |
dc.identifier.doi | 10.1016/j.actbio.2019.01.048 | pt_PT |
dc.identifier.essn | 1878-7568 | pt_PT |
Appears in Collections: | CICECO - Artigos DEMaC - Artigos |
Files in This Item:
File | Description | Size | Format | |
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Robocasting of Cu2+ & La3+ doped sol–gel glass scaffolds with greatly enhanced.pdf | 2.01 MB | Adobe PDF | View/Open |
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