Please use this identifier to cite or link to this item:
Title: An Overview on the Recent Advances in Alternative Solvents as Stabilizers of Proteins and Enzymes
Author: Almeida, Jéssica S.
Capela, Emanuel V.
Loureiro, Ana M.
Tavares, Ana P. M.
Freire, Mara G.
Issue Date: Aug-2022
Publisher: MDPI
Abstract: Currently, the use of alternative solvents is increasing, namely ionic liquids (ILs) and deep eutectic solvents (DESs) in diverse fields of knowledge, such as biochemistry, chemistry, chemical engineering, biotechnology and biomedicine. Particularly, when compared to traditional solvents, these alternative solvents have great importance for biomolecules due to the enhanced solubility, structure stability and the biological activity of biomolecules, such as protein and enzymes. Thus, in this review article, the recent developments and efforts on the technological developments carried out with ILs and DESs for the stabilization and activation of proteins and enzymes are provided. The most studied IL-and DES-based formulations for proteins and enzymes are discussed and the molecular mechanisms and interactions related to the increased stability promoted by these alternative solvents are disclosed, while emphasizing their main advantages
Peer review: yes
DOI: 10.3390/chemengineering6040051
ISSN: 2305-7084
Appears in Collections:CICECO - Artigos
DQ - Artigos

Formato BibTex MendeleyEndnote Degois 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.