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http://hdl.handle.net/10773/34724
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DC Field | Value | Language |
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dc.contributor.author | Nunes, B. | pt_PT |
dc.contributor.author | Leal, C. | pt_PT |
dc.contributor.author | Rodrigues, S. | pt_PT |
dc.contributor.author | Antunes, S. C. | pt_PT |
dc.date.accessioned | 2022-09-22T09:09:14Z | - |
dc.date.available | 2022-09-22T09:09:14Z | - |
dc.date.issued | 2018-07 | - |
dc.identifier.issn | 0273-1223 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10773/34724 | - |
dc.description.abstract | Antibiotics (e.g. ciprofloxacin) have been detected in surface water and groundwater for several decades. In order to understand the potential impact of the continuous exposure of aquatic organisms to ciprofloxacin, a chronic assay was carried out with Daphnia magna. This approach allowed evaluation of the effects of ciprofloxacin on life-history and sub-individual parameters (antioxidant status and metabolic response: activities of catalase and glutathione S-transferases - GSTs; peroxidative damage; thiobarbituric acid reactive substances and genotoxic effects (genetic damage index, measured by the comet assay). Life-history parameters of D. magna showed no significant effects after ciprofloxacin exposure. Concerning oxidative stress and metabolism parameters, no significant alterations were reported for catalase and GSTs activities. However, a dual response was observed, with a significant decrease in lipid peroxidation levels at low ciprofloxacin concentrations (<0.013 mg/L), while a significant increase was verified at high ciprofloxacin concentrations (0.078 mg/L). The genotoxicity assay detected a significant increase in genetic damage index up to 0.013 mg/L of ciprofloxacin. The here-tested ciprofloxacin concentrations, which are ecologically relevant, did not cause significant impacts concerning the life-history parameters of D. magna; however, at the same levels of ciprofloxacin an oxidative stress and genotoxic damage scenarios were recorded. | pt_PT |
dc.language.iso | eng | pt_PT |
dc.publisher | IWA Publishing | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F04423%2F2013/PT | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FAMB%2F50017%2F2019/PT | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/FARH/SFRH%2FBPD%2F109951%2F2015/PT | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/FARH/SFRH%2FBD%2F84061%2F2012/PT | pt_PT |
dc.rights | openAccess | pt_PT |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | pt_PT |
dc.subject | Antibiotics | pt_PT |
dc.subject | Chronic assays | pt_PT |
dc.subject | Comet assay; | pt_PT |
dc.subject | Fluoroquinolones | pt_PT |
dc.subject | Oxidative stress biomarkers | pt_PT |
dc.subject | Reproductive parameters | pt_PT |
dc.title | Assessment of ecotoxicological effects of ciprofloxacin in Daphnia magna: life-history traits, biochemical and genotoxic effects | pt_PT |
dc.type | article | pt_PT |
dc.description.version | published | pt_PT |
dc.peerreviewed | yes | pt_PT |
degois.publication.firstPage | 835 | pt_PT |
degois.publication.issue | 3 | pt_PT |
degois.publication.lastPage | 844 | pt_PT |
degois.publication.title | Water Science and Technology | pt_PT |
degois.publication.volume | 2017 | pt_PT |
dc.identifier.doi | 10.2166/wst.2018.255 | pt_PT |
Appears in Collections: | CESAM - Artigos DBio - Artigos |
Files in This Item:
File | Description | Size | Format | |
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nunes2018.pdf | 359.3 kB | Adobe PDF | View/Open |
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