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http://hdl.handle.net/10773/31044
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Prada-Ramallal, Guillermo | pt_PT |
dc.contributor.author | Roque, Fátima | pt_PT |
dc.contributor.author | Herdeiro, Maria Teresa | pt_PT |
dc.contributor.author | Takkouche, Bahi | pt_PT |
dc.contributor.author | Figueiras, Adolfo | pt_PT |
dc.date.accessioned | 2021-03-26T11:27:11Z | - |
dc.date.available | 2021-03-26T11:27:11Z | - |
dc.date.issued | 2018-09 | - |
dc.identifier.issn | 1471-2288 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10773/31044 | - |
dc.description.abstract | The data from individual observational studies included in meta-analyses of drug effects are collected either from ad hoc methods (i.e. "primary data") or databases that were established for non-research purposes (i.e. "secondary data"). The use of secondary sources may be prone to measurement bias and confounding due to over-the-counter and out-of-pocket drug consumption, or non-adherence to treatment. In fact, it has been noted that failing to consider the origin of the data as a potential cause of heterogeneity may change the conclusions of a meta-analysis. We aimed to assess to what extent the origin of data is explored as a source of heterogeneity in meta-analyses of observational studies. | pt_PT |
dc.language.iso | eng | pt_PT |
dc.publisher | BMC | pt_PT |
dc.rights | openAccess | pt_PT |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | pt_PT |
dc.subject | Drug | pt_PT |
dc.subject | Heterogeneity | pt_PT |
dc.subject | Meta-analysis | pt_PT |
dc.subject | Observational studies | pt_PT |
dc.subject | Out-of-pocket | pt_PT |
dc.subject | Over-the-counter | pt_PT |
dc.subject | Source of data | pt_PT |
dc.title | Primary versus secondary source of data in observational studies and heterogeneity in meta-analyses of drug effects: a survey of major medical journals | pt_PT |
dc.type | article | pt_PT |
dc.description.version | published | pt_PT |
dc.peerreviewed | yes | pt_PT |
degois.publication.issue | 1 | pt_PT |
degois.publication.title | BMC Medical Research Methodology | pt_PT |
degois.publication.volume | 18 | pt_PT |
dc.identifier.doi | 10.1186/s12874-018-0561-3 | pt_PT |
dc.identifier.essn | 1471-2288 | pt_PT |
Appears in Collections: | IBIMED - Artigos DCM - Artigos |
Files in This Item:
File | Description | Size | Format | |
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artigo.pdf | 684.52 kB | Adobe PDF | View/Open |
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