Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/27430
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dc.contributor.authorPirone, Giuliopt_PT
dc.contributor.authorCoppola, Francescapt_PT
dc.contributor.authorPretti, Carlopt_PT
dc.contributor.authorSoares, Amadeu M. V. M.pt_PT
dc.contributor.authorSolé, Montserratpt_PT
dc.contributor.authorFreitas, Rosapt_PT
dc.date.accessioned2020-01-30T15:13:23Z-
dc.date.issued2019-06-
dc.identifier.issn0305-0491pt_PT
dc.identifier.urihttp://hdl.handle.net/10773/27430-
dc.description.abstractInterest on the effects of emerging contaminants over aquatic organisms has increased in the last years. Nonetheless, the toxic action of classical natural and anthropogenically-driven metals has also to be monitored, especially because they reflect real environmental situations. For that, in the present study we focused on the effects on the marine mussel Mytilus galloprovincialis of the personal care product Triclosan (TCS) and Lead (Pb), as toxic metal, under separate and co-exposure situations at environmentally relevant concentrations: TCS (1 μg/L) and Pb (50 μg/L). The consideration of an additional factor such as an increase in ambient temperature was also included to provide a forecasted scenario of climate change: from the ambient temperature at actual conditions (17 °C) to a predicted warming situation (22 °C). Water chemical characterization and some physical properties and bioaccumulation of TCS and Pb in mussels at the end of the experiment (28 days) was considered. The parameters followed up comprise the energy related system production (electron transport system) and glycogen and protein reserves. Antioxidant enzymatic defences towards reactive oxygen species (ROS) and the consequences of ROS damage over endogenous lipids (LPO) and proteins (PC). Overall the results suggested only particular responses to chemical exposures at 17 °C whereas at 22 °C the detoxification machinery was set up and this prevented the occurrence of LPO. Nonetheless, PC formation occurred under Pb and TCS + Pb co-exposure at the highest temperature. Due to the complexity of the study: 4 chemical conditions, 2 temperatures and 10 biomarkers considered, a principal component ordination (PCO) analysis was included. The results of this integrative analysis confirmed a clear effect of the temperature, more responsiveness to drugs at 22 °C and in all likelihood due to Pb presence.pt_PT
dc.language.isoengpt_PT
dc.publisherElsevierpt_PT
dc.relationPTDC/CTA-AMB/28425/2017pt_PT
dc.relationSFRH/BD/118582/2016pt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/147273/PTpt_PT
dc.relationCGL2016-76332-Rpt_PT
dc.rightsembargoedAccesspt_PT
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMytilus galloprovincialispt_PT
dc.subjectWarmingpt_PT
dc.subjectPersonal care productspt_PT
dc.subjectMetalspt_PT
dc.subjectOxidative stresspt_PT
dc.subjectMetabolismpt_PT
dc.titleThe effect of temperature on Triclosan and Lead exposed musselspt_PT
dc.typearticlept_PT
dc.description.versionpublishedpt_PT
dc.peerreviewedyespt_PT
degois.publication.firstPage42pt_PT
degois.publication.lastPage50pt_PT
degois.publication.titleComparative Biochemistry and Physiology - B: Comparative Biochemistrypt_PT
degois.publication.volume232pt_PT
dc.date.embargo2020-07-01-
dc.identifier.doi10.1016/j.cbpb.2019.02.007pt_PT
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DBio - Artigos

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