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Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/25456
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dc.contributor.authorCaetano, Tâniapt_PT
dc.contributor.authorKrawczyk, Joanna M.pt_PT
dc.contributor.authorMösker, Evapt_PT
dc.contributor.authorSüssmuth, Roderich D.pt_PT
dc.contributor.authorMendo, Sóniapt_PT
dc.date.accessioned2019-02-28T10:46:17Z-
dc.date.available2019-02-28T10:46:17Z-
dc.date.issued2011-
dc.identifier.issn0099-2240pt_PT
dc.identifier.urihttp://hdl.handle.net/10773/25456-
dc.description.abstractThis study demonstrated, for the first time, that immunity genes licFGEHI are not essential for selfprotection and production of the two-component lantibiotic lichenicidin in the Gram-negative heterologous host Escherichia coli BLic5. Additionally, it was experimentally demonstrated that lichenicidin lantibiotics are active against the E. coli imp4213 strain, a mutant strain possessing a permeable outer membrane.pt_PT
dc.description.sponsorshipThe work was supported by the Centre for Environmental and Marine Studies (CESAM) of the University of Aveiro and the Cluster of Excellence “Unifying Concepts in Catalysis” granted by the DFG, coordinated by TU Berlin. We acknowledge José C. Duarte for supplying the B. licheniformis I89 strain, Thomas J. Silhavy from Princeton University for supplying the E. coli MC4100 and E. coli imp4213 strains, and Klaus Hantke from the University of Tübingen for supplying the E. coli BW25113 and BW25113ΔtolC::kan strains.pt_PT
dc.language.isoengpt_PT
dc.publisherAmerican Society for Microbiologypt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBDE%2F15559%2F2005/PTpt_PT
dc.rightsrestrictedAccesspt_PT
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleLichenicidin biosynthesis in Escherichia coli: licFGEHI immunity genes are not essential for lantibiotic production or self-protectionpt_PT
dc.typearticlept_PT
dc.description.versionpublishedpt_PT
dc.peerreviewedyespt_PT
degois.publication.firstPage5023pt_PT
degois.publication.issue14pt_PT
degois.publication.lastPage5026pt_PT
degois.publication.titleApplied and Environmental Microbiologypt_PT
degois.publication.volume77pt_PT
dc.identifier.doi10.1128/AEM.00270-11pt_PT
dc.identifier.essn1098-5336pt_PT
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