Please use this identifier to cite or link to this item:
http://hdl.handle.net/10773/20998
Title: | PDMS-SiO2-TiO2-CaO hybrid materials - Cytocompatibility and nanoscale surface features |
Author: | Carlos Almeida, J. Wacha, Andras Gomes, Pedro S. Fernandes, M. Helena R. Helena Vaz Fernandes, M. Miranda Salvado, Isabel M. |
Keywords: | NUCLEAR-MAGNETIC-RESONANCE POLYDIMETHYLSILOXANE (PDMS)-CAO-SIO2 HYBRIDS MESOPOROUS BIOACTIVE GLASSES SILOXANE-OXIDE MATERIALS SMALL-ANGLE SCATTERING SOL-GEL MATERIALS X-RAY-SCATTERING STATE SI-29 NMR CELL-ADHESION STRUCTURAL-CHARACTERIZATION |
Issue Date: | 2016 |
Publisher: | ELSEVIER SCIENCE BV |
Abstract: | Two PDMS-SiO2-TiO2-Cao porous hybrid materials were prepared using the same base composition, precursors, and solvents, but following two different sol-gel procedures, based on the authors' previous works where for the first time, in this hybrid system, calcium acetate was used as calcium source. The two different procedures resulted in monolithic materials with different structures, microstructures, and surface wettability. Even though both are highly hydrophobic (contact angles of 127.2 degrees and 150.6 degrees), and present different filling regimes due to different surface topographies, they have demonstrated to be-cytocompatible when tested with human osteoblastic cells, against the accepted idea that high-hydrophobic surfaces are not suitable to cell adhesion and proliferation. At the nanoscale, the existence of hydrophilic silica domains containing calcium, where water molecules are physisorbed, is assumed to support this capability, as discussed. (C) 2016 Elsevier B.V. All rights reserved. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/20998 |
DOI: | 10.1016/j.msec.2016.03.071 |
ISSN: | 0928-4931 |
Publisher Version: | 10.1016/j.msec.2016.03.071 |
Appears in Collections: | CICECO - Artigos |
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PDMS-SiO2-TiO2-CaO hybrid materials - Cytocompatibility and nanoscale surface features_10.1016j.msec.2016.03.071.pdf | 2.02 MB | Adobe PDF |
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