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|Title:||Do bacterial cellulose membranes have potential in drug-delivery systems?|
|Author:||Silvestre, Armando J. D.|
Freire, Carmen S. R.
Neto, Carlos P.
|Keywords:||BIOMIMETIC MINERALIZATION SYNTHESIS|
|Abstract:||Introduction: Bacterial cellulose (BC) is an extremely pure form of cellulose, which, due to its unique properties, such as high purity, water-holding capacity, three-dimensional nanofibrilar network, mechanical strength, biodegradability and biocompatibility, shows a high potential as nanomaterial in a wide range of high-tech domains including biomedical applications, and most notably in controlled drug-delivery systems. Areas covered: This appraisal is intended to cover the major characteristics of BC, followed by the key aspects of BC production both in static and agitated conditions, and a glance of the major applications of BC, giving some emphasis to biomedical applications. Finally, a detailed discussion of the different applications of BC in controlled drug-delivery systems will be put forward, with focus on topical and oral drug-delivery systems, using either native BC or composite materials thereof. Expert opinion: The limited number of studies carried out so far demonstrated that BC, or materials prepared from it, are interesting materials for drug-delivery systems. There is, however, a large field of systematic research ahead to develop new and more selectively responsive materials and eventually to conjugate them with other biomedical applications of BC under development.|
|Appears in Collections:||CICECO - Artigos|
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|Do bacterial cellulose membranes have potential in drug-delivery systems_10.151717425247.2014.920819.pdf||277.98 kB||Adobe PDF|
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