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Title: Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study
Author: Cabral, Luís
Afreixo, Vera
Meireles, Rita
Vaz, Miguel
Marques, Margarida
Tourais, Isabel
Chaves, Catarina
Almeida, Luís
Paiva, José Artur
Keywords: Burns
Issue Date: 5-Sep-2018
Publisher: BMC
Abstract: Early sepsis diagnosis is crucial for the correct management of burn patients, and it clearly influences outcomes. The systemic inflammatory response triggered by burns mimics sepsis presentation and complicates early sepsis diagnosis. Biomarkers were advocated to aid the diagnosis of early sepsis. Serum procalcitonin (PCT) exhibits fair accuracy and good correlation with sepsis severity, being used in diverse clinical settings. However, few studies have evaluated perioperative changes in PCT levels in burn patients. The present study evaluated PCT kinetics during the first days after burn injury and subsequent surgical interventions to assess PCT utility in distinguishing septic from non-septic inflammatory responses.
Peer review: yes
DOI: 10.1186/s12871-018-0585-6
Appears in Collections:CIDMA - Artigos
PSG - Artigos

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