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http://hdl.handle.net/10773/20723
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DC Field | Value | Language |
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dc.contributor.author | Pinol, Rafael | pt |
dc.contributor.author | Brites, Carlos D. S. | pt |
dc.contributor.author | Bustamante, Rodney | pt |
dc.contributor.author | Martinez, Abelardo | pt |
dc.contributor.author | Silva, Nuno J. O. | pt |
dc.contributor.author | Murillo, Jose L. | pt |
dc.contributor.author | Cases, Rafael | pt |
dc.contributor.author | Carrey, Julian | pt |
dc.contributor.author | Estepa, Carlos | pt |
dc.contributor.author | Sosa, Cecilia | pt |
dc.contributor.author | Palacio, Fernando | pt |
dc.contributor.author | Carlos, Luis D. | pt |
dc.contributor.author | Millan, Angel | pt |
dc.date.accessioned | 2017-12-07T19:57:10Z | - |
dc.date.issued | 2015 | pt |
dc.identifier.issn | 1936-0851 | pt |
dc.identifier.uri | http://hdl.handle.net/10773/20723 | - |
dc.description.abstract | Whereas efficient and sensitive nanoheaters and nanothermometers are demanding tools, in modern bio- and nanomedicine, joining both features in a single nanoparticle still remains a real challenge, despite the recent progress achieved, Most Of it Within the last year. Here we demonstrate a successful realization of this challenge. The heating is magnetically induced, the temperature readout is optical, and the ratiometric thermometric probes are dual-emissive Eu3+/Tb3+ lanthanide complexes. The low thermometer heat capacitance (0.021 center dot K-1) and heater/thermometer resistance (1 K center dot W-1), the high temperature sensitivity (5.8%center dot K-1 at 296 K) and uncertainty (0.5 K), the physiological working temperature range (295-315 K), the readout reproducibility (>99.5%), and the fast time response (0.250 s) make the heater/thermometer nanoplatform proposed here unique. Cells were incubated with the nanoparticles, and fluorescence microscopy permits the mapping of the intracellular local temperature using the pixel-by-pixel ratio of the Eu3+/Tb3+ intensities. Time-resolved thermometry under an ac magnetic field evidences the failure of using Macroscopic thermal parameters to describe heat diffusion at the nanoscale. | pt |
dc.language.iso | eng | pt |
dc.publisher | AMER CHEMICAL SOC | pt |
dc.relation | info:eu-repo/grantAgreement/FCT/5876/147332/PT | pt |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F89003%2F2012/PT | pt |
dc.rights | restrictedAccess | por |
dc.subject | IRON-OXIDE NANOPARTICLES | pt |
dc.subject | MOLECULAR THERMOMETER | pt |
dc.subject | LIVING CELLS | pt |
dc.subject | TEMPERATURE | pt |
dc.subject | HYPERTHERMIA | pt |
dc.subject | NANOSCALE | pt |
dc.subject | FIELD | pt |
dc.title | Joining Time-Resolved Thermometry and Magnetic-Induced Heating in a Single Nanoparticle Unveils Intriguing Thermal Properties | pt |
dc.type | article | pt |
dc.peerreviewed | yes | pt |
ua.distribution | international | pt |
degois.publication.firstPage | 3134 | pt |
degois.publication.issue | 3 | pt |
degois.publication.lastPage | 3142 | pt |
degois.publication.title | ACS NANO | pt |
degois.publication.volume | 9 | pt |
dc.date.embargo | 10000-01-01 | - |
dc.relation.publisherversion | 10.1021/acsnano.5b00059 | pt |
dc.identifier.doi | 10.1021/acsnano.5b00059 | pt |
Appears in Collections: | CICECO - Artigos |
Files in This Item:
File | Description | Size | Format | |
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Joining Time-Resolved Thermometry and Magnetic-Induced Heating in a Single Nanoparticle Unveils Intriguing Thermal Properties_10.1021acsnano.5b00059.pdf | 3.42 MB | Adobe PDF |
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