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http://hdl.handle.net/10773/20682| Title: | An easy synthetic access to new pyrazole spiro derivatives from 3-amino-1-phenyl-2-pyrazolin-5-one |
| Author: | Zaiter, Jamila Achibat, Hanane Amiri, Ouafa Hafid, Abderrafia Khouili, Mostafa Rakib, El Mostapha Neves, Claudia M. B. Neves, Maria Graca P. M. S. Silva, Artur M. S. Cavaleiro, Jose A. S. Almeida Paz, Filipe A. Faustino, Maria Amparo F. |
| Keywords: | CONDENSATION |
| Issue Date: | 2015 |
| Publisher: | ROYAL SOC CHEMISTRY |
| Abstract: | Pyrazole and pyrazolone moieties have shown important biological activities. For this reason, the synthesis of new derivatives has attracted interest from the scientific community. Herein we report the formation of two unexpected spiro compounds containing pyrazole moieties using a tandem process involving the initial condensation of 3-amino-1-phenyl-2-pyrazolin-5-one with benzaldehyde followed by dimerization. |
| Peer review: | yes |
| URI: | http://hdl.handle.net/10773/20682 |
| DOI: | 10.1039/c5nj01306b |
| ISSN: | 1144-0546 |
| Publisher Version: | 10.1039/c5nj01306b |
| Appears in Collections: | CICECO - Artigos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| An easy synthetic access to new pyrazole spiro derivatives from 3-amino-1-phenyl-2-pyrazolin-5-one_10.1039c5nj01306b.pdf | 718.54 kB | Adobe PDF |  |
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