Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/20662
Title: Targeting Cancer Cells with Photoactive Silica Nanoparticles
Author: Borzecka, Wioleta
Trindade, Tito
Torres, Tomas
Tome, Joao
Keywords: THERAPY IN-VITRO
UP-CONVERSION NANOPARTICLES
SINGLET OXYGEN GENERATION
IRON-OXIDE NANOPARTICLES
PHOTODYNAMIC THERAPY
DRUG-DELIVERY
PHOTOPHYSICAL PROPERTIES
BIOMEDICAL APPLICATIONS
COMBINED CHEMOTHERAPY
HYBRID NANOPARTICLES
Issue Date: 2016
Publisher: BENTHAM SCIENCE PUBL LTD
Abstract: This review highlights recent advances in the preparation of silica nanoparticles (SNPs) functionalized with porphyrins and phthalocyanines for application in cancer photo-diagnostic and photodynamic therapy (PDT). The use of photosensitizer-SNP formulations has emerged recently as a new nanomedicine for cancer research owing to their unique physicochemical properties, which make them useful for photo-biomedical applications. In order to study their photobiological properties, diverse chemical strategies involving covalent and non-covalent bonding have been used to load photosensitizers in/on SNPs.
Peer review: yes
URI: http://hdl.handle.net/10773/20662
DOI: 10.2174/1381612822666160614083804
ISSN: 1381-6128
Publisher Version: 10.2174/1381612822666160614083804
Appears in Collections:CICECO - Artigos

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