Please use this identifier to cite or link to this item:
http://hdl.handle.net/10773/35092
Title: | Physical tests are poorly related to patient-reported outcome measures during severe acute exacerbations of COPD |
Author: | Quadflieg, Kirsten Machado, Ana Haesevoets, Sarah Daenen, Marc Thomeer, Michiel Ruttens, David Spruit, Martijn A Burtin, Chris |
Keywords: | Chronic obstructive pulmonary disease Acute exacerbations Exercise capacity Muscle function Patient-reported outcome measures |
Issue Date: | 28-Dec-2021 |
Publisher: | MDPI |
Abstract: | Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have a negative impact on patients' health status, including physical function and patient-reported outcomes. We aimed to explore the associations between physical tests and patient-reported outcome measures (PROMs) in hospitalised patients for an AECOPD. Patients were assessed on the day of discharge. Quadriceps force, handgrip strength, short physical performance battery (SPPB), five-repetition sit-to-stand test (5STS), four-meter gait speed test (4MGS), balance test, six-minute walk test (6MWT), COPD Assessment Test (CAT), London Chest Activity of Daily Living scale (LCADL), modified Medical Research Council (mMRC) dyspnea scale, Checklist of Individual Strength (CIS)-fatigue subscale, and Patient Health Questionnaire (PHQ-9) were collected. Sixty-nine patients with an AECOPD were included (54% female; age 69 ± 9 years; FEV1 39.2 (28.6-49.1%) predicted). Six-minute walk distance was strongly correlated with mMRC (ρ: -0.64, p < 0.0001) and moderately correlated with LCADL total score, subscales self-care and household activities (ρ ranging from -0.40 to -0.58, p < 0.01). Moreover, 4MGS was moderately correlated with mMRC (ρ: -0.49, p < 0.0001). Other correlations were weak or non-significant. During a severe AECOPD, physical tests are generally poorly related to PROMs. Therefore, a comprehensive assessment combining both physical tests and PROMs needs to be conducted in these patients to understand their health status. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/35092 |
DOI: | 10.3390/jcm11010150 |
Publisher Version: | https://www.mdpi.com/2077-0383/11/1/150 |
Appears in Collections: | Lab3R - Artigos |
Files in This Item:
File | Description | Size | Format | |
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jcm-11-00150.pdf | 255.08 kB | Adobe PDF | View/Open |
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