Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10773/28740
Título: | Tailoring carbon nanotubes surface chemistry for the purification of antileukemic drugs |
Autor: | Barros, Maria A. Almeida, Mafalda R. Faria, Joaquim L. Sampaio, Maria J. Tavares, Ana P. M. Silva, Cláudia G. |
Palavras-chave: | Carbon nanotubes Antileukemic drugs L-asparaginase Purification |
Data: | Jun-2019 |
Resumo: | Biopharmaceuticals have been used to overcome fatal diseases related with aging. L-aspariginase (LA), in particular, has shown evidences of being efficient for leukemia therapy. The LA production and purification require several steps increasing the cost of the process. In this work, functionalized carbon nanotubes (CNTs) were studied as a cost-effective support to purify LA. It was shown that CNTs have strong affinity for the target biopharmaceutical, meaning that can be a promising alternative for the adsorption and purification of LA. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/28740 |
Aparece nas coleções: | CICECO - Comunicações |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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DCE_abstract_MAB.pdf | 179.95 kB | Adobe PDF | Ver/Abrir |
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