Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/21153
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dc.contributor.authorDias, Lídia C. A.pt
dc.contributor.authorSoares, Amadeu M. V. M.pt
dc.contributor.authorFerreira, Abel L. G.pt
dc.contributor.authorSantos, Cátia S.pt
dc.contributor.authorMonteiro, Marta S.pt
dc.date.accessioned2017-12-13T16:12:45Z-
dc.date.issued2014-
dc.identifier.issn0025-326Xpt
dc.identifier.urihttp://hdl.handle.net/10773/21153-
dc.description.abstractThe presence of endocrine disruptor chemicals (EDCs) in aquatic compartments, including estuaries, has been object of major concern. However, the effects of EDCs on autochthonous estuarine fish species are far less known than in freshwater fish. Therefore, the response of biomarkers in the estuarine fish Pomatoschistus microps was evaluated after 21-days of exposure to different EDCs: 17β-estradiol (E2); PCB-77 and p,p'DDE. In juveniles, Vtg (vitellogenin)-like proteins were significantly induced by E2. PCB-77 led to a decrease of Vtg-like proteins in juveniles, while in female liver they increased at the highest concentrations tested, suggesting a mode of action of PCB-77 that depends on the fish life stage. p,p'-DDE did not induce significant changes in Vtg-like proteins. Overall, P. microps juveniles seemed to respond to environmental relevant concentrations of EDCs. Thus, the evaluation of Vtg-like proteins in this life stage seems to be a promising tool to track EDC contamination in biomonitoring studies.pt
dc.language.isoengpt
dc.publisherElsevierpt
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F45911%2F2008/PTpt
dc.relationinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/104379/PTpt
dc.rightsrestrictedAccesspor
dc.subject17β-Estradiolpt
dc.subjectCommon gobypt
dc.subjectGonadosomatic indexpt
dc.subjectP,p'-DDEpt
dc.subjectPCB-77pt
dc.subjectVitellogeninpt
dc.titleBiomarkers of endocrine disruption in juveniles and females of the estuarine fish Pomatoschistus micropspt
dc.typearticle
dc.peerreviewedyespt
ua.distributioninternationalpt
degois.publication.firstPage314pt
degois.publication.issue1-2
degois.publication.lastPage321pt
degois.publication.titleMarine Pollution Bulletinpt
degois.publication.volume84pt
dc.date.embargo10000-01-01-
dc.identifier.doi10.1016/j.marpolbul.2014.04.040pt
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