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http://hdl.handle.net/10773/6216
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DC Field | Value | Language |
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dc.contributor.author | Daniel-da-Silva, Ana L | pt |
dc.contributor.author | Fateixa, Sara | pt |
dc.contributor.author | Guiomar, António J | pt |
dc.contributor.author | Costa, Benilde F O | pt |
dc.contributor.author | Silva, Nuno J O | pt |
dc.contributor.author | Trindade, Tito | pt |
dc.contributor.author | Goodfellow, Brian J | pt |
dc.contributor.author | Gil, Ana M | pt |
dc.date.accessioned | 2012-02-10T15:20:58Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1361-6528 | pt |
dc.identifier.uri | http://hdl.handle.net/10773/6216 | - |
dc.description.abstract | Magnetic hydrogel κ-carrageenan nanospheres were successfully prepared via water-in-oil (w/o) microemulsions combined with thermally induced gelation of the polysaccharide. The size of the nanospheres (an average diameter ( ) of about 50 and 75 nm) was modulated by varying the concentration of surfactant. The nanospheres contained superparamagnetic magnetite nanoparticles ( 8 nm), previously prepared by co-precipitation within the biopolymer. Carboxyl groups, at a concentration of about 4 mmol g−1, were successfully grafted at the surface of these magnetic nanospheres via carboxymethylation of the κ-carrageenan. The carboxylated nanospheres were shown to be thermo-sensitive in the 37–45 ◦C temperature range, indicating their potential as thermally controlled delivery systems for drugs and/or magnetic particles at physiological temperatures. Finally, preliminary results have been obtained for IgG antibody conjugation of the carboxylated nanospheres and the potential of these systems for bio-applications is discussed. | pt |
dc.language.iso | eng | pt |
dc.publisher | Institute of Physics | pt |
dc.rights | restrictedAccess | por |
dc.title | Biofunctionalized magnetic hydrogel nanospheres of magnetite and k-carrageenan | pt |
dc.type | article | pt |
dc.peerreviewed | yes | pt |
ua.distribution | international | pt |
degois.publication.firstPage | 1 | pt |
degois.publication.issue | 35 | - |
degois.publication.issue | 35 | pt |
degois.publication.lastPage | 10 | pt |
degois.publication.title | Nanotechnology | pt |
degois.publication.volume | 20 | pt |
dc.date.embargo | 10000-01-01 | - |
dc.identifier.doi | 10.1088/0957-4484/20/35/355602 | * |
Appears in Collections: | DQ - Artigos |
Files in This Item:
File | Description | Size | Format | |
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Nanotechnology 20 (2009) 355602 (10pp.pdf | 1.28 MB | Adobe PDF |
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