Circuit modeling of rGO-doped scaffolds for spinal cord regeneration based on transient and AC analyses

Abstract

Circuit modeling of scaffolds based on porcine adipose decellularized extracellular matrix (adECM) doped with reduced graphene oxide (rGO) for spinal cord regeneration is presented. The characteristics of the scaffolds capped with silver electrodes were studied in an aqueous medium through transient and AC analyses. In addition, cyclic voltammetry (CV) plots were obtained. The transient measurements were done using a custom current driver while the CV and AC measurements were obtained with an external impedance analyzer. The results revealed that incorporating rGO reduced the series resistance and the impedance at low frequencies of the scaffold.