Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/36041
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dc.contributor.authorAlmeida, Tâniapt_PT
dc.contributor.authorMoreira, Patríciapt_PT
dc.contributor.authorSousa, Fábio J.pt_PT
dc.contributor.authorPereira, Cláudiapt_PT
dc.contributor.authorSilvestre, Armando J. D.pt_PT
dc.contributor.authorVilela, Carlapt_PT
dc.contributor.authorFreire, Carmen S. R.pt_PT
dc.date.accessioned2023-01-26T18:20:02Z-
dc.date.available2023-01-26T18:20:02Z-
dc.date.issued2022-03-
dc.identifier.issn1996-1944pt_PT
dc.identifier.urihttp://hdl.handle.net/10773/36041-
dc.description.abstractBacterial nanocellulose (BNC) membranes, with remarkable physical and mechanical properties, emerged as a versatile biopolymeric carrier of bioactive compounds for skin care applications. In this study, BNC membranes were loaded with glycerol (as plasticizer and humectant agent) and different doses (1–3 μg cm−2) of an aqueous extract obtained from the hydro-distillation of Eucalyptus globulus Labill. leaves (HDE), for application as sheet facial masks. All membranes are resistant and highly malleable at dry and wet states, with similar or even better mechanical properties than those of a commercial BNC mask. Moreover, the HDE was found to confer a dose-dependent antioxidant activity to pure BNC. Additionally, upon 3 months of storage at 22–25 °C and 52% relative humidity (RH) or at 40 °C and 75% RH, it was confirmed that the antioxidant activity and the macroscopic aspect of the membrane with 2 μg cm−2 of HDE were maintained. Membranes were also shown to be non-cytotoxic towards HaCaT and NIH/3T3 cells, and the membrane with 2 μg cm−2 of HDE caused a significant reduction in the senescence-associated β-galactosidase activity in NIH/3T3 cells. These findings suggest the suitability and potential of the obtained membranes as bioactive facial masks for anti-aging applications.pt_PT
dc.language.isoengpt_PT
dc.publisherMDPIpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50011%2F2020/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50011%2F2020/PTpt_PT
dc.relationLA/P/0006/2020pt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/CEEC IND 2018/CEECIND%2F00263%2F2018%2FCP1559%2FCT0018/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/CEEC IND4ed/2021.01571.CEECIND%2FCP1659%2FCT0024/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/CEEC IND 2017/CEECIND%2F00464%2F2017%2FCP1459%2FCT0033/PTpt_PT
dc.rightsopenAccesspt_PT
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBacterial nanocellulosept_PT
dc.subjectEucalyptus globulus Labillpt_PT
dc.subjectLeavespt_PT
dc.subjectAqueous extractpt_PT
dc.subjectAntioxidant activitypt_PT
dc.subjectSheet facial maskspt_PT
dc.subjectAnti-agingpt_PT
dc.subjectSkin care applicationspt_PT
dc.titleBioactive bacterial nanocellulose membranes enriched with eucalyptus globulus labill. leaves aqueous extract for anti-aging skin care applicationspt_PT
dc.typearticlept_PT
dc.description.versionpublishedpt_PT
dc.peerreviewedyespt_PT
degois.publication.issue5pt_PT
degois.publication.titleMaterialspt_PT
degois.publication.volume15pt_PT
dc.relation.publisherversionhttps://www.mdpi.com/1996-1944/15/5/1982pt_PT
dc.identifier.doi10.3390/ma15051982pt_PT
dc.identifier.articlenumber1982pt_PT
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