Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/34486
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dc.contributor.authorPedro, Sónia N.pt_PT
dc.contributor.authorFreire, Carmen S. R.pt_PT
dc.contributor.authorSilvestre, Armando J. D.pt_PT
dc.contributor.authorFreire, Mara G.pt_PT
dc.date.accessioned2022-08-30T16:24:02Z-
dc.date.available2022-08-30T16:24:02Z-
dc.date.issued2021-04-01-
dc.identifier.urihttp://hdl.handle.net/10773/34486-
dc.description.abstractIonic liquids (ILs) are molten salts composed of a large organic cation and an organic/inorganic anion. Due to their ionic character, most ILs present advantageous properties over conventional solvents, such as negligible volatility at atmospheric conditions and high thermal and chemical stabilities. The wide variety of IL anion–cation combinations allows these solvents to be designed to display a strong solvation ability for a myriad of active pharmaceutical ingredients (APIs) and (bio)polymers. Given these properties, ILs have been used as solvents and as formulation components in different areas of drug delivery, as well as novel liquid forms of APIs (API-ILs) applied in different stages of development of novel drug delivery systems. Furthermore, their combination with polymers and biopolymers has enabled the design of drug delivery systems for new therapeutic routes of administration.pt_PT
dc.language.isoengpt_PT
dc.publisherMDPIpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50011%2F2020/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50011%2F2020/PTpt_PT
dc.relationPOCI-01-0145-FEDER-031106pt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBTA-BTA%2F31106%2F2017/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F132584%2F2017/PTpt_PT
dc.rightsopenAccesspt_PT
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectActive pharmaceutical ingredientspt_PT
dc.subjectDrug deliverypt_PT
dc.subjectFormulationspt_PT
dc.subjectIonic liquidspt_PT
dc.subjectPermeation enhancerspt_PT
dc.subjectStimuli-responsive systemspt_PT
dc.titleIonic liquids in drug deliverypt_PT
dc.typearticlept_PT
dc.description.versionpublishedpt_PT
dc.peerreviewedyespt_PT
degois.publication.firstPage324pt_PT
degois.publication.issue2pt_PT
degois.publication.lastPage339pt_PT
degois.publication.titleEncyclopediapt_PT
degois.publication.volume1pt_PT
dc.identifier.doi10.3390/encyclopedia1020027pt_PT
dc.identifier.essn2673-8392pt_PT
Appears in Collections:CICECO - Artigos
DQ - Artigos

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