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Title: Monthly follow-Ups of functional status in people with COPD: a longitudinal study
Author: Rocha, Vânia
Cabral, Jorge
Souto-Miranda, Sara
Machado, Ana Filipa
Jácome, Cristina
Cruz, Joana
Martins, Vitória
Simão, Paula
Mendes, Maria Aurora
Afreixo, Vera
Marques, Alda
Keywords: COPD
Evaluation and monitoring
Field tests
Functional status
One-minute sit-to-stand test
Issue Date: 1-Jun-2022
Publisher: MDPI
Abstract: Functional status is an important and meaningful outcome in people with chronic obstructive pulmonary disease (COPD), although its measurement is not embedded in routine clinical assessments. This study described the functional status of people with COPD using the 1-min sitto-stand test (1minSTS) over a 6-month period and the examined sociodemographic and clinical characteristics associated with this outcome. Data from a prospective study including people with COPD were analyzed. Functional status was assessed monthly with the 1minSTS over 6 months. Linear-mixed effect models assessed the 1minSTS number of repetitions mean change. One-hundred and eight participants (82.4% men; 66.9 ± 9.5 years) were included. A significantly lower number of repetitions in the 1minSTS over the 6-month period was associated with being female (estimate: −4.69, 95%CI: −8.20; −1.18), being older (estimate: −0.56, 95%CI: −0.77; −0.34), having higher BMI (estimate: −0.55, 95%CI: −0.81; −0.28) and having higher activity-related dyspnea (estimate: −2.04, 95%CI: −3.25; −0.83). Half of the participants showed improvements above three repetitions in the 1minSTS over the 6-month period, independently of their baseline impairment (1minSTS < 70% predicted: 52.5%; ≥70% predicted: 54.4%). To conclude, monthly follow-up assessments were associated with clinically relevant benefits in the functional status of people with COPD. Age, body composition, and activity-related dyspnea were the main predictors of functional status over time. Further research is needed to corroborate our findings and to support the beneficial effects of regular COPD monitoring.
Peer review: yes
DOI: 10.3390/jcm11113052
ISSN: 2077-0383
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