Please use this identifier to cite or link to this item:
http://hdl.handle.net/10773/32742
Title: | Advantages of porcine xenograft over autograft in sinus lift: a randomised clinical trial |
Author: | Correia, Francisco Pozza, Daniel Humberto Gouveia, Sónia Felino, António Campos Faria-Almeida, Ricardo |
Keywords: | Bone grafting Bone regeneration Bone substitutes Sinus augmentation Sinus floor augmentation Split mouth randomised clinical trial |
Issue Date: | 21-Jun-2021 |
Publisher: | MDPI |
Abstract: | This study aimed to compare the performance of intra-oral autologous bone grafts versus porcine xenografts in a two-step lateral window sinus lift. This split-mouth randomised controlled trial sequentially enrolled 12 patients with a 6-month follow-up. For each patient, a simultaneous randomised bilateral maxillary sinus lift was performed and filled with autologous bone from the mandible (control) or a porcine xenograft (test). A bone biopsy sample was collected during the implant placement for histological and histomorphometric analysis. CT scans were performed at the beginning and at the end of the trial to assess radiological evolution. A comparison of initial and six-month CT scans indicated statistically significant increases in bone level for both materials (7.8 ± 2.4 mm for autologous and 8.7 ± 2.2 mm for xenograft, p < 0.05), and there were no significant differences between the performance of the two materials over time (p = 0.26). The histological analysis showed various stages of the remodelling process and no cells or other signs of inflammation or infection were visible in both groups. The porcine xenografts presented similar results for the studied variables when compared to autologous bone, being a reasonable alternative for a sinus lift. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/32742 |
DOI: | 10.3390/ma14123439 |
ISSN: | 1996-1944 |
Publisher Version: | https://www.mdpi.com/1996-1944/14/12/3439 |
Appears in Collections: | DETI - Artigos IEETA - Artigos |
Files in This Item:
File | Description | Size | Format | |
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2021 Correia et al Materials.pdf | 3.93 MB | Adobe PDF | View/Open |
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