Please use this identifier to cite or link to this item:
Title: Exposure to mercury and human reproductive health: a systematic review
Author: Henriques, Magda Carvalho
Loureiro, Susana
Fardilha, Margarida
Herdeiro, Maria Teresa
Keywords: Epidemiology
Human fertility
Mercury exposure
Systematic review
Issue Date: Apr-2019
Publisher: Elsevier
Abstract: Background Evidences from human and animal studies suggest that reproductive function may be affected by mercury. The aim of this review was to explore the mercury influence on human fertility. Methods A systematic search was made in PubMED for papers published between 1975–2017, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results Increased mercury levels were associated with infertility or subfertility status. Further, infertile subjects with unexplained infertility showed higher levels of mercury in hair, blood and urine than fertile ones. Mercury exposure induced sperm DNA damage and abnormal sperm morphology and motility. Additionally, mercury levels were related with higher incidence of menstrual and hormonal disorders and increased rates of adverse reproductive outcomes. Conclusions Our review showed that mercury negatively impacts human reproduction, affecting the reproductive and endocrine systems in both male and female. However, the molecular mechanisms underlying the mercury-associated decline on fertility remains unknown.
Peer review: yes
DOI: 10.1016/j.reprotox.2019.02.012
ISSN: 0890-6238
Appears in Collections:CESAM - Artigos
IBIMED - Artigos
DBio - Artigos
DCM - Artigos

Files in This Item:
File Description SizeFormat 
mercury_male_reproductive_health_draft.pdf593.2 kBAdobe PDFView/Open

Formato BibTex MendeleyEndnote Degois 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.