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Title: Tailoring carbon nanotubes surface chemistry for the purification of antileukemic drugs
Author: Barros, Maria A.
Almeida, Mafalda R.
Faria, Joaquim L.
Sampaio, Maria J.
Tavares, Ana P. M.
Silva, Cláudia G.
Keywords: Carbon nanotubes
Antileukemic drugs
Issue Date: Jun-2019
Abstract: Biopharmaceuticals have been used to overcome fatal diseases related with aging. L-aspariginase (LA), in particular, has shown evidences of being efficient for leukemia therapy. The LA production and purification require several steps increasing the cost of the process. In this work, functionalized carbon nanotubes (CNTs) were studied as a cost-effective support to purify LA. It was shown that CNTs have strong affinity for the target biopharmaceutical, meaning that can be a promising alternative for the adsorption and purification of LA.
Peer review: yes
Appears in Collections:CICECO - Comunicações

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