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Title: Does salinity modulates the response of Mytilus galloprovincialis exposed to triclosan and diclofenac?
Author: Freitas, Rosa
Coppola, Francesca
Costa, Silvana
Manzini, Chiara
Intorre, Luigi
Meucci, Valentina
Soares, Amadeu M. V. M.
Pretti, Carlo
Solé, Montserrat
Keywords: Pharmaceuticals and personal care products
Oxidative stress
Energy metabolism
Extreme weather events
Issue Date: Aug-2019
Publisher: Elsevier
Abstract: In the present study Mytilus galloprovincialis mussels were exposed for 28 days to three salinities: 30 (control), 25 and 35. Simultaneously, organisms at each salinity were exposed to either the antimicrobial agent Triclosan (TCS) or the pharmaceutical drug Diclofenac (DIC) at 1 μg/L. Salinity alone and exposure to PPCPs changed mussel's metabolic capacity and oxidative status, but no additive or synergetic effects resulting from the combined exposures were observed. Overall, the metabolic capacity of mussels was decreased when exposed to TCS and DIC under control salinity, which was less pronounced at salinities out of the control level. TCS had a notorious effect over glutathione peroxidase activity while DIC exposure enhanced catalase response. Such defence mechanisms were able to prevent cellular damage but still a clear reduction in GSH/GSSG ratio after PPCPs exposures indicates oxidative stress which could compromise bivalve's performance to further stressing events.
Peer review: yes
DOI: 10.1016/j.envpol.2019.04.115
ISSN: 0269-7491
Appears in Collections:CESAM - Artigos
DBio - Artigos

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