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http://hdl.handle.net/10773/27161
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DC Field | Value | Language |
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dc.contributor.author | Lopes, I. | pt_PT |
dc.contributor.author | Ribeiro, R. | pt_PT |
dc.contributor.author | Antunes, F. E. | pt_PT |
dc.contributor.author | Rocha-Santos, T. A. P. | pt_PT |
dc.contributor.author | Rasteiro, M. G. | pt_PT |
dc.contributor.author | Soares, A. M. V. M. | pt_PT |
dc.contributor.author | Gonçalves, F. | pt_PT |
dc.contributor.author | Pereira, R. | pt_PT |
dc.date.accessioned | 2019-12-12T14:27:12Z | - |
dc.date.available | 2019-12-12T14:27:12Z | - |
dc.date.issued | 2012-04 | - |
dc.identifier.issn | 0963-9292 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10773/27161 | - |
dc.description.abstract | The present work aimed at evaluating the toxicity and genotoxicity of two organic (vesicles composed of sodium dodecyl sulphate/didodecyl dimethylammonium bromide-SDS/DDAB and of monoolein and sodium oelate-Mo/NaO) and four inorganic (titanium oxide-TiO₂, silicon titanium-TiSiO₄, Lumidot-CdSe/ZnS, and gold nanorods) nanoparticles (NP), suspended in two aqueous media (Milli Q water and American Society for Testing and Materials (ASTM) hardwater), to the bacteria Vibrio fischeri (Microtox test) and Salmonella typhimurium-his⁻ (Ames test with strains TA98 and TA100). Aiming a better understanding of these biological responses physical and chemical characterization of the studied NP suspensions was carried out. Results denoted a high aggregation state of the NP in the aqueous suspensions, with the exception of SDS/DDAB and Mo/NaO vesicles, and of nanogold suspended in Milli Q water. This higher aggregation was consistent with the low values of zeta potential, revealing the instability of the suspensions. Regarding toxicity data, except for nano TiO₂, the tested NP significantly inhibited bioluminescence of V. fischeri. Genotoxic effects were only induced by SDS/DDAB and TiO₂ for the strain TA98. A wide range of toxicity responses was observed for the six tested NP, differing by more than 5 orders of magnitude, and suggesting different modes of action of the tested NP. | pt_PT |
dc.language.iso | eng | pt_PT |
dc.publisher | Springer | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F26801%2F2006/PT | pt_PT |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F65410%2F2009/PT | pt_PT |
dc.rights | restrictedAccess | pt_PT |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | pt_PT |
dc.subject | Microtox test | pt_PT |
dc.subject | Ames test | pt_PT |
dc.subject | Nanoparticles | pt_PT |
dc.subject | Zeta potential | pt_PT |
dc.subject | DLS | pt_PT |
dc.title | Toxicity and genotoxicity of organic and inorganic nanoparticles to the bacteria Vibrio fischeri and Salmonella typhimurium | pt_PT |
dc.type | article | pt_PT |
dc.description.version | published | pt_PT |
dc.peerreviewed | yes | pt_PT |
degois.publication.firstPage | 637 | pt_PT |
degois.publication.issue | 3 | pt_PT |
degois.publication.lastPage | 648 | pt_PT |
degois.publication.title | Ecotoxicology | pt_PT |
degois.publication.volume | 21 | pt_PT |
dc.identifier.doi | 10.1007/s10646-011-0808-9 | pt_PT |
dc.identifier.essn | 1573-3017 | pt_PT |
Appears in Collections: | CESAM - Artigos DBio - Artigos DQ - Artigos |
Files in This Item:
File | Description | Size | Format | |
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Lopes et al. - 2012 - Toxicity and genotoxicity of organic and inorganic.pdf | 342.9 kB | Adobe PDF |
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