Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/27161
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dc.contributor.authorLopes, I.pt_PT
dc.contributor.authorRibeiro, R.pt_PT
dc.contributor.authorAntunes, F. E.pt_PT
dc.contributor.authorRocha-Santos, T. A. P.pt_PT
dc.contributor.authorRasteiro, M. G.pt_PT
dc.contributor.authorSoares, A. M. V. M.pt_PT
dc.contributor.authorGonçalves, F.pt_PT
dc.contributor.authorPereira, R.pt_PT
dc.date.accessioned2019-12-12T14:27:12Z-
dc.date.available2019-12-12T14:27:12Z-
dc.date.issued2012-04-
dc.identifier.issn0963-9292pt_PT
dc.identifier.urihttp://hdl.handle.net/10773/27161-
dc.description.abstractThe present work aimed at evaluating the toxicity and genotoxicity of two organic (vesicles composed of sodium dodecyl sulphate/didodecyl dimethylammonium bromide-SDS/DDAB and of monoolein and sodium oelate-Mo/NaO) and four inorganic (titanium oxide-TiO₂, silicon titanium-TiSiO₄, Lumidot-CdSe/ZnS, and gold nanorods) nanoparticles (NP), suspended in two aqueous media (Milli Q water and American Society for Testing and Materials (ASTM) hardwater), to the bacteria Vibrio fischeri (Microtox test) and Salmonella typhimurium-his⁻ (Ames test with strains TA98 and TA100). Aiming a better understanding of these biological responses physical and chemical characterization of the studied NP suspensions was carried out. Results denoted a high aggregation state of the NP in the aqueous suspensions, with the exception of SDS/DDAB and Mo/NaO vesicles, and of nanogold suspended in Milli Q water. This higher aggregation was consistent with the low values of zeta potential, revealing the instability of the suspensions. Regarding toxicity data, except for nano TiO₂, the tested NP significantly inhibited bioluminescence of V. fischeri. Genotoxic effects were only induced by SDS/DDAB and TiO₂ for the strain TA98. A wide range of toxicity responses was observed for the six tested NP, differing by more than 5 orders of magnitude, and suggesting different modes of action of the tested NP.pt_PT
dc.language.isoengpt_PT
dc.publisherSpringerpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F26801%2F2006/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F65410%2F2009/PTpt_PT
dc.rightsrestrictedAccesspt_PT
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMicrotox testpt_PT
dc.subjectAmes testpt_PT
dc.subjectNanoparticlespt_PT
dc.subjectZeta potentialpt_PT
dc.subjectDLSpt_PT
dc.titleToxicity and genotoxicity of organic and inorganic nanoparticles to the bacteria Vibrio fischeri and Salmonella typhimuriumpt_PT
dc.typearticlept_PT
dc.description.versionpublishedpt_PT
dc.peerreviewedyespt_PT
degois.publication.firstPage637pt_PT
degois.publication.issue3pt_PT
degois.publication.lastPage648pt_PT
degois.publication.titleEcotoxicologypt_PT
degois.publication.volume21pt_PT
dc.identifier.doi10.1007/s10646-011-0808-9pt_PT
dc.identifier.essn1573-3017pt_PT
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