Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/25224
Title: Feasibility of computerized adventitious respiratory sounds to assess the effects of airway clearance techniques in patients with bronchiectasis
Author: Herrero-Cortina, Beatriz
Oliveira, Ana
Polverino, Eva
Gómez-Trullén, Eva María
Torres, Antoni
Marques, Alda
Keywords: Physical therapy
Bronchiectasis
Respiratory sounds
Rehabilitation
Airway clearance techniques
Issue Date: 23-Jan-2019
Publisher: Taylor & Francis
Abstract: Objective: To examine the feasibility of adventitious respiratory sound (ARS) as an outcome measure to assess the effects of airway clearance techniques (ACTs) in outpatients with bronchiectasis. Methods: ARS were registered pre/post four ACTs sessions. Clinical outcomes included: number of crackles (coarse and fine), number of wheezes (monophonic and polyphonic), wheezes occupation rate (%) and sputum quantity. Feasibility outcomes of ARS included: reasons for exclusion, suitability, safety, equipment and time required, magnitude of change after intervention and sample size estimation. Results: Seven patients (49.7 ± 20.5 years; FEV1 69.3 ± 15.8% predicted) were included. Recordings from four patients were excluded due to excessive environment noise. All ARS measurements were completed without any adverse events. An electronic stethoscope was acquired and the time spent to complete each assessment was 6 ± 3.5 min. The largest changes were observed for number of expiratory coarse crackles [effect size (95%CI) ES = 0.40 (0.01–0.79)], which correlated moderately with sputum quantity (r = 0.56), and inspiratory monophonic wheezes [ES = 0.61 (0.22–1.00)]. The estimated sample size for a full crossover trial was 46. Conclusions: ARS is feasible to assess the effects of ACTs in patients with bronchiectasis. Expiratory coarse crackles seem to be the most appropriate ARS parameter, but this finding needs to be confirmed in an adequately powered trial.
Peer review: yes
URI: http://hdl.handle.net/10773/25224
DOI: 10.1080/09593985.2019.1566945
ISSN: 0959-3985
Publisher Version: https://www.tandfonline.com/doi/full/10.1080/09593985.2019.1566945
Appears in Collections:Lab3R - Artigos

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