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Title: Parameter estimation, sensitivity analysis and optimal control of a periodic epidemic model with application to HRSV in Florida
Author: Rosa, Silvério
Torres, Delfim F. M.
Keywords: Human Respiratory Syncytial Virus (HRSV)
Compartmental Mathematical Models
Estimation of Parameters
Optimal Control
Issue Date: 29-Mar-2018
Publisher: International Academic Press
Abstract: A state wide Human Respiratory Syncytial Virus (HRSV) surveillance system was implemented in Florida in 1999 to support clinical decision-making for prophylaxis of premature infants. The research presented in this paper addresses the problem of fitting real data collected by the Florida HRSV surveillance system by using a periodic SEIRS mathematical model. A sensitivity and cost-effectiveness analysis of the model is done and an optimal control problem is formulated and solved with treatment as the control variable.
Peer review: yes
DOI: 10.19139/soic.v6i1.472
ISSN: 2311-004X
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Appears in Collections:SCG - Artigos

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