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http://hdl.handle.net/10773/23683
Título: | Biochemical and metabolic effects of a short-term exposure to nanoparticles of titanium silicate in tadpoles of Pelophylax perezi (Seoane) |
Autor: | Salvaterra, T. Alves, M. G. Domingues, I. Pereira, R. Rasteiro, M. G. Carvalho, R. A. Soares, A. M. V. M. Lopes, I. |
Palavras-chave: | 1H NMR analysis Nanomaterials Oxidative stress Pelophylax perezi TiSiO4 |
Data: | 2013 |
Editora: | Elsevier |
Resumo: | This study aimed to evaluate sublethal effects of a short-term exposure (96h) to titanium silicate nanoparticles (TiSiO4-NP) on Pelophylax perezi tadpoles. Tadpoles were exposed to five concentrations of TiSiO4-NP (8.2, 10.2, 12.8, 16 and 20mg/L) plus a control. Effect criteria were: mortality, cholinesterases, glutathione S-transferases, lactate dehydrogenase, and catalase activities, and alanine and lactate contents. Light scattering was used for physical characterization of TiSiO4-NP suspensions, revealing a high aggregation state of the NP, consistent with low z-potential values (<30mV). Mortality among TiSiO4-NP treatments was <11%. Significant differences relatively to the control were observed at the biochemical level (for CAT and LDH) and in lactate and alanine contents, which may end-up in increased oxidative stress. Overall, some of the monitored endpoints suggest metabolic alterations in TiSiO4-NP exposed tadpoles, highlighting the potential of TiSiO4-NP long-term effects on these organisms. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/23683 |
DOI: | 10.1016/j.aquatox.2012.12.014 |
ISSN: | 0166-445X |
Aparece nas coleções: | CESAM - Artigos DBio - Artigos |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Salvaterra et al. - 2013 - Biochemical and metabolic effects of a short-term .pdf | 204.33 kB | Adobe PDF |
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