Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/20897
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dc.contributor.authorDomingues, Rui M. A.pt
dc.contributor.authorGuerra, Angela R.pt
dc.contributor.authorDuarte, M.pt
dc.contributor.authorFreire, Carmen S. R.pt
dc.contributor.authorNeto, Carlos P.pt
dc.contributor.authorSilva, Carlos M. S.pt
dc.contributor.authorSilvestre, Arnando J. D.pt
dc.date.accessioned2017-12-07T20:03:17Z-
dc.date.issued2014pt
dc.identifier.issn1570-193Xpt
dc.identifier.urihttp://hdl.handle.net/10773/20897-
dc.description.abstractThis review aims to provide an overview of the biogenetic origin of triterpenic acids (with particular emphasis on ursolic, oleanolic and betulinic acids), on the analytical extraction and hyphenated methodologies (mainly GC-MS) used on their identification and quantification, followed by an overview of the major sources of these components, indicating their potential large scale production pathways, with especial emphasis on abundant agroforestry biomass residues. The biological activity of ursolic, oleanolic and betulinic acids is described, focusing on their antitumoral potential as modulators of growth inhibitory signals, evasion of apoptosis and angiogenesis. The future perspectives towards improved therapeutic strategies using these triterpenic acids are also herein discussed.pt
dc.language.isoengpt
dc.publisherBENTHAM SCIENCE PUBL LTDpt
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/228589/EUpt
dc.relationinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F98635%2F2013/PTpt
dc.relationinfo:eu-repo/grantAgreement/FCT/COMPETE/132936/PTpt
dc.rightsrestrictedAccesspor
dc.subjectBREAST-CANCER CELLSpt
dc.subjectPERFORMANCE LIQUID-CHROMATOGRAPHYpt
dc.subjectSUPERCRITICAL-FLUID EXTRACTIONpt
dc.subjectEUCALYPTUS-GLOBULUS BARKpt
dc.subjectMOLECULARLY-IMPRINTED POLYMERSpt
dc.subjectLIGHT-SCATTERING DETECTIONpt
dc.subjectTETRA-CYCLIC TRITERPENESpt
dc.subjectPOROUS GRAPHITIC CARBONpt
dc.subjectLIGUSTRUM-LUCIDUM AITpt
dc.subjectANTI-HIV ACTIVITYpt
dc.titleBioactive Triterpenic Acids: From Agroforestry Biomass Residues to Promising Therapeutic Toolspt
dc.typearticlept
dc.peerreviewedyespt
ua.distributioninternationalpt
degois.publication.firstPage382pt
degois.publication.issue3pt
degois.publication.lastPage399pt
degois.publication.titleMINI-REVIEWS IN ORGANIC CHEMISTRYpt
degois.publication.volume11pt
dc.date.embargo10000-01-01-
dc.relation.publisherversionhttp://www.eurekaselect.com/115374/articlept
Appears in Collections:CICECO - Artigos

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