Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/20897
Title: Bioactive Triterpenic Acids: From Agroforestry Biomass Residues to Promising Therapeutic Tools
Author: Domingues, Rui M. A.
Guerra, Angela R.
Duarte, M.
Freire, Carmen S. R.
Neto, Carlos P.
Silva, Carlos M. S.
Silvestre, Arnando J. D.
Keywords: BREAST-CANCER CELLS
PERFORMANCE LIQUID-CHROMATOGRAPHY
SUPERCRITICAL-FLUID EXTRACTION
EUCALYPTUS-GLOBULUS BARK
MOLECULARLY-IMPRINTED POLYMERS
LIGHT-SCATTERING DETECTION
TETRA-CYCLIC TRITERPENES
POROUS GRAPHITIC CARBON
LIGUSTRUM-LUCIDUM AIT
ANTI-HIV ACTIVITY
Issue Date: 2014
Publisher: BENTHAM SCIENCE PUBL LTD
Abstract: This review aims to provide an overview of the biogenetic origin of triterpenic acids (with particular emphasis on ursolic, oleanolic and betulinic acids), on the analytical extraction and hyphenated methodologies (mainly GC-MS) used on their identification and quantification, followed by an overview of the major sources of these components, indicating their potential large scale production pathways, with especial emphasis on abundant agroforestry biomass residues. The biological activity of ursolic, oleanolic and betulinic acids is described, focusing on their antitumoral potential as modulators of growth inhibitory signals, evasion of apoptosis and angiogenesis. The future perspectives towards improved therapeutic strategies using these triterpenic acids are also herein discussed.
Peer review: yes
URI: http://hdl.handle.net/10773/20897
ISSN: 1570-193X
Publisher Version: http://www.eurekaselect.com/115374/article
Appears in Collections:CICECO - Artigos

Files in This Item:
File Description SizeFormat 
Bioactive triterpenic acids From agroforestry biomass residues to promising therapeutic tools_.pdf576.33 kBAdobe PDFrestrictedAccess


FacebookTwitterLinkedIn
Formato BibTex MendeleyEndnote Degois 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.