Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/20649
Title: A One-Pot Diastereoselective Synthesis of 2-[Aryl(hydroxy)methyl]-6-methyl-2H-furo[3,2-c]pyran-3,4-diones: Crystallographic Evidence for the Furanone Ring Closure
Author: Abdi, Yamina
Boutemeur-Kheddis, Baya
Hamdi, Maamar
Talhi, Oualid
Paz, Filipe A. Almeida
Kirsch, Gilbert
Silva, Artur M. S.
Keywords: STEREOSELECTIVE-SYNTHESIS
MULTICOMPONENT APPROACH
DERIVATIVES SYNTHESIS
BIOLOGICAL-ACTIVITY
DEHYDROACETIC ACID
PENICILLIUM-SP
AMINES
CYCLIZATION
FLAVANONES
FLAVONOIDS
Issue Date: 2015
Publisher: GEORG THIEME VERLAG KG
Abstract: Novel furopyran-3,4-dione-fused heterocycles have been obtained by a one-pot reaction of -brominated dehydroacetic acid and benzaldehydes under organobase conditions. The prepared 2-[aryl(hydroxy)methyl]-6-methyl-2H-furo[3,2-c]pyran-3,4-diones were fully characterized by 2D NMR spectroscopy and supported by single-crystal X-ray analysis to unequivocally prove the furan-3-one five-membered ring-closure mechanism instead of the dihydroflavanon-3-ol six-membered cyclization which has recently been proposed in the literature.
Peer review: yes
URI: http://hdl.handle.net/10773/20649
DOI: 10.1055/s-0034-1380214
ISSN: 0936-5214
Publisher Version: 10.1055/s-0034-1380214
Appears in Collections:CICECO - Artigos



FacebookTwitterLinkedIn
Formato BibTex MendeleyEndnote Degois 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.