Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10773/20043
Título: | Fluorescent Magnetic Bioprobes by Surface Modification of Magnetite Nanoparticles |
Autor: | Pinheiro, Paula C. Daniel-da-Silva, Ana L. Tavares, Daniela S. Pilar Calatayud, M. Goya, Gerardo F. Trindade, Tito |
Palavras-chave: | IRON-OXIDE NANOPARTICLES DRUG-DELIVERY BIOMEDICAL APPLICATIONS INTRACELLULAR UPTAKE SILICA SPHERES PARTICLES LUMINESCENT CELLS LAYER |
Data: | 2013 |
Editora: | MDPI AG |
Resumo: | Bimodal nanoprobes comprising both magnetic and optical functionalities have been prepared via a sequential two-step process. Firstly, magnetite nanoparticles (MNPs) with well-defined cubic shape and an average dimension of 80 nm were produced by hydrolysis of iron sulfate and were then surface modified with silica shells by using the sol-gel method. The Fe3O4@SiO2 particles were then functionalized with the fluorophore, fluorescein isothiocyanate (FITC), mediated by assembled shells of the cationic polyelectrolyte, polyethyleneimine (PEI). The Fe3O4 functionalized particles were then preliminary evaluated as fluorescent and magnetic probes by performing studies in which neuroblast cells have been contacted with these nanomaterials. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/20043 |
DOI: | 10.3390/ma6083213 |
ISSN: | 1996-1944 |
Versão do Editor: | 10.3390/ma6083213 |
Aparece nas coleções: | CICECO - Artigos |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Fluorescent Magnetic Bioprobes by Surface Modification of Magnetite Nanoparticles_10.3390ma6083213.pdf | 630.58 kB | Adobe PDF | Ver/Abrir |
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