Please use this identifier to cite or link to this item: http://hdl.handle.net/10773/19368
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSilva, Nuno H. C. S.pt
dc.contributor.authorDrumond, Inespt
dc.contributor.authorAlmeida, Isabel F.pt
dc.contributor.authorCosta, Paulopt
dc.contributor.authorRosado, Catarina F.pt
dc.contributor.authorNeto, Carlos Pascoalpt
dc.contributor.authorFreire, Carmen S. R.pt
dc.contributor.authorSilvestre, Armando J. D.pt
dc.date.accessioned2017-12-07T19:10:22Z-
dc.date.issued2014pt
dc.identifier.issn0969-0239pt
dc.identifier.urihttp://hdl.handle.net/10773/19368-
dc.description.abstractIn this study, biocellulose (BC) membranes have been investigated as caffeine topical delivery systems, for the potential treatment of cellulite. BC-caffeine membranes were prepared by a simple approach and the permeation of caffeine through human epidermis, from BC or from conventional formulation systems (solution and gel), was compared in vitro to assess their therapeutic applicability. Diffusion studies with Franz cells showed that the incorporation of caffeine in BC membranes provided lower permeation rates than those obtained with the conventional formulations. These results combined with the possibility of producing BC membranes with different shapes demonstrate that these materials are promising biosystems for topical delivery of caffeine, showing reproducibility and an extended and predictable caffeine release over time, leading to their potential use for cellulite attenuation.pt
dc.language.isoengpt
dc.publisherSPRINGERpt
dc.relationinfo:eu-repo/grantAgreement/FCT/COMPETE/132936/PTpt
dc.rightsrestrictedAccesspor
dc.subjectIN-VITRO DIFFUSIONpt
dc.subjectBACTERIAL CELLULOSEpt
dc.subjectBIOMATERIALSpt
dc.subjectFIBROBLASTSpt
dc.subjectLIDOCAINEpt
dc.subjectIBUPROFENpt
dc.subjectPOLYMERSpt
dc.subjectRELEASEpt
dc.subjectWOUNDSpt
dc.subjectSKINpt
dc.titleTopical caffeine delivery using biocellulose membranes: a potential innovative system for cellulite treatmentpt
dc.typearticlept
dc.peerreviewedyespt
ua.distributioninternationalpt
degois.publication.firstPage665pt
degois.publication.issue1pt
degois.publication.lastPage674pt
degois.publication.titleCELLULOSEpt
degois.publication.volume21pt
dc.date.embargo10000-01-01-
dc.relation.publisherversion10.1007/s10570-013-0114-1pt
dc.identifier.doi10.1007/s10570-013-0114-1pt
Appears in Collections:CICECO - Artigos



FacebookTwitterLinkedIn
Formato BibTex MendeleyEndnote Degois 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.