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Title: Deposition, structure, physical and invitro characteristics of Ag-doped beta-Ca-3(PO4)(2)/chitosan hybrid composite coatings on Titanium metal
Author: Singh, Ram Kishore
Awasthi, Sharad
Dhayalan, Arunkumar
Ferreira, J.M.F.
Kannan, S.
Keywords: Silver
Ti metal
Issue Date: 2016
Publisher: Elsevier
Abstract: Pure and five silver-doped (0-5Ag) β-tricalcium phosphate [β-TCP, β-Ca3(PO4)2]/chitosan composite coatings were deposited on Titanium (Ti) substrates and their properties that are relevant for applications in hard tissue replacements were assessed. Silver, β-TCP and chitosan were combined to profit from their salient and complementary antibacterial and biocompatible features.The β-Ca3(PO4)2 powders were synthesized by co-precipitation. The characterization results confirmed the Ag+ occupancy at the crystal lattice of β-Ca3(PO4)2. The Ag-dopedβ-Ca3(PO4)2/chitosan composite coatings deposited by electrophoresis showed good antibacterial activity and exhibited negative cytotoxic effects towards the human osteosarcoma cell line MG-63. The morphology of the coatings was observed by SEM and their efficiency against corrosion of metallic substrates was determined through potentiodynamic polarization tests.
Peer review: yes
DOI: 10.1016/j.msec.2016.02.013
ISSN: 0928-4931
Appears in Collections:CICECO - Artigos

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