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http://hdl.handle.net/10773/18152| Title: | Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering |
| Author: | Pereira, Susana R Sanchez i Nogue, Violeta Frazao, Cludio J R Serafim, Luisa S Gorwa-Grauslund, Marie F Xavier, Ana M R B |
| Keywords: | Hardwood spent sulfite liquor (HSSL) Scheffersomyces stipitis Lignocellulosic inhibitors Evolutionary engineering Bioethanol |
| Issue Date: | 2015 |
| Publisher: | Biomes Central |
| Abstract: | Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtain variants of S. stipitis with increased tolerance to HSSL inhibitors while maintaining the ability to ferment xylose to ethanol. |
| Peer review: | yes |
| URI: | http://hdl.handle.net/10773/18152 |
| DOI: | 10.1186/s13068-015-0234-y |
| ISSN: | 1754-6834 |
| Appears in Collections: | CICECO - Artigos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering_10.1186s13068-015-0234-y.pdf | 932.09 kB | Adobe PDF | View/Open |
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