Please use this identifier to cite or link to this item:
http://hdl.handle.net/10773/16472
Title: | Seasonality effects on dengue: basic reproduction number, sensitivity analysis and otpimal control |
Author: | Rodrigues, Helena Sofia Monteiro, M. Teresa T. Torres, Delfim F. M. |
Keywords: | Dengue Vectorial capacity Seasonality Basic reproduction number Sensitivity analysis Optimal control |
Issue Date: | Nov-2016 |
Publisher: | Wiley Online Library |
Abstract: | Dengue is a vector-borne disease transmitted from an infected human to an Aedes mosquito, during a blood-meal. Dengue is still a major public health problem. A model for the disease transmission is presented, composed by human and mosquitoes compartments. The aim is to simulate the effects of seasonality, on the vectorial capacity and, consequently, on the disease development. Using entomological information about the mosquito behavior under different temperatures and rainfall, simulations are carried out and the repercussions analyzed. The basic reproduction number of the model is given, as well as a sensitivity analysis of model's parameters. Finally, an optimal control problem is proposed and solved, illustrating the difficulty of making a trade-off between reduction of infected individuals and costs with insecticide. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/16472 |
DOI: | 10.1002/mma.3319 |
ISSN: | 0170-4214 |
Appears in Collections: | CIDMA - Artigos SCG - Artigos |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
2016_seasonality effetcs dengue_VERSAO FINAL EDITORA.pdf | documento Principal | 314.85 kB | Adobe PDF |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.