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http://hdl.handle.net/10773/20418
Title: | NMR metabolomics of renal cancer: an overview |
Author: | Gil, Ana M. de Pinho, Paula Guedes Monteiro, Marcia S. Duarte, Iola F. |
Keywords: | MAGNETIC-RESONANCE-SPECTROSCOPY SPECTROMETRY-BASED METABOLOMICS CHRONIC KIDNEY-DISEASE CELL CARCINOMA-CELLS BIOMARKER DISCOVERY PROSTATE-CANCER HUMAN SERUM HEPATOCELLULAR-CARCINOMA COLORECTAL-CANCER METABONOMICS |
Issue Date: | 2015 |
Publisher: | FUTURE SCI LTD |
Abstract: | This paper reviews the use of NMR metabolomics for the metabolic characterization of renal cancer. The existing challenges in the clinical management of this disease are first presented, followed by a brief introduction to the metabolomics approach, in the context of cancer research. A subsequent review of the literature on NMR metabolic studies of renal cancer reveals that the subject has been clearly underdeveloped, compared with other types of cancer, particularly regarding cultured cells and tissue analysis. NMR analysis of biofluids has focused on blood (plasma or serum) metabolomics, comprising no account of studies on human urine, in spite of its noninvasiveness and physiological proximity to the affected organs. Finally, some areas of potential future development are identified. |
Peer review: | yes |
URI: | http://hdl.handle.net/10773/20418 |
DOI: | 10.4155/bio.15.167 |
ISSN: | 1757-6180 |
Publisher Version: | 10.4155/bio.15.167 |
Appears in Collections: | CICECO - Artigos |
Files in This Item:
File | Description | Size | Format | |
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NMR metabolomics of renal cancer an overview_10.4155bio.15.167.pdf | 487.67 kB | Adobe PDF |
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